Regeneration

Pluripotency  or   “Cell Potency”    https://en.wikipedia.org/wiki/Cell_potency                According to Latin terms, Pluripotentia means the ability for many things.

These cells generate into any of the three Germ Layers

  • Endodermal cells
  • Mesodermal cells
  • Ectodermal cells

EXCEPT TISSUES LIKE THE PLACENTA       what????

 

We can generate Induced Pluripotent cells by using the Induced pluripotency technique by

Triggering or Expressing the genes or                        (difference)

transcription factors of the normal somatic cells       (what are transciption factors?)

 iPSC   induced pluripotent ? cells

IPS  induced pluripotent ?

 

Regeneration

So We can forcefully express the transcription factors like  Oct4Sox2Klf4, and c-Myc[1] of a non-pluripotent cell and convert them into a stem cell.

and develop a Human pluripotent cell from a Human epidermal fibroblast cell.

But because

“Though the iPSC has similar properties to embryonic stem cells they were never approved for clinical stage research because they are highly Tumerogenic, having low replication rates and early senescence.”

 

 

Though the iPSC has similar properties to embryonic stem cells they were never approved for clinical stage research because they are highly Tumerogenic, having low replication rates and early senescence.

 

 

Notes

RNase  =  Possibly the little “rn” you have been seeing oddly..

  1. the condition or process of deterioration with age.
    • loss of a cell’s power of division and growth.

Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for producing messenger RNA (mRNA), which directs the synthesis of a protein.

(AN-tee-sents …) Small pieces of DNA that can bind to specific molecules of RNA and block the cell’s ability to use the RNA to make a protein or work in other ways. Antisense DNA may be used to block the production of proteins needed for cell growth.